I46F (p.Ile46Phe) variant of IFNAR1 (Interferon alpha/beta receptor 1)
I46F (p.Ile46Phe) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
I46F (p.Ile46Phe) variant details
- p.Ile46Phe
- gnomAD 21-33335583-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.16
- MetaLR 0.33
- MetaSVM -0.75
- CADD 10.50
- PolyPhen-2 0.01
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available