I41T (p.Ile41Thr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
I41T (p.Ile41Thr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
I41T (p.Ile41Thr) variant details
- p.Ile41Thr
- gnomAD 21-33335569-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.22
- MetaLR 0.46
- MetaSVM -0.82
- CADD 20.90
- PolyPhen-2 0.86
- SIFT 0.33
- Population evidence available
- Structural context available
- Literature evidence available