G57E (p.Gly57Glu) variant of IFNAR1 (Interferon alpha/beta receptor 1)
G57E (p.Gly57Glu) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
G57E (p.Gly57Glu) variant details
- p.Gly57Glu
- gnomAD 21-33335617-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.12
- MetaLR 0.20
- MetaSVM -0.88
- CADD 0.70
- PolyPhen-2 0.27
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available