G26R (p.Gly26Arg) variant of IFNAR1 (Interferon alpha/beta receptor 1)
G26R (p.Gly26Arg) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
G26R (p.Gly26Arg) variant details
- p.Gly26Arg
- gnomAD 21-33325131-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.53
- MetaLR 0.55
- MetaSVM 0.14
- CADD 35.00
- PolyPhen-2 1.00
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available