F63L (p.Phe63Leu) variant of IFNAR1 (Interferon alpha/beta receptor 1)
F63L (p.Phe63Leu) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
F63L (p.Phe63Leu) variant details
- p.Phe63Leu
- gnomAD 21-33335636-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.11
- MetaLR 0.15
- MetaSVM -1.03
- CADD 17.20
- PolyPhen-2 0.03
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available