F45L (p.Phe45Leu) variant of IFNAR1 (Interferon alpha/beta receptor 1)
F45L (p.Phe45Leu) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
F45L (p.Phe45Leu) variant details
- p.Phe45Leu
- ExAC rs751075101
- gnomAD rs751075101
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.34
- MetaLR 0.43
- MetaSVM -0.55
- CADD 21.80
- PolyPhen-2 0.95
- SIFT 0.03
- Population evidence available
- Structural context available