E37K (p.Glu37Lys) variant of IFNAR1 (Interferon alpha/beta receptor 1)
E37K (p.Glu37Lys) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
E37K (p.Glu37Lys) variant details
- p.Glu37Lys
- ExAC rs764413583
- TOPMed rs764413583
- gnomAD rs764413583
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.13
- MetaLR 0.24
- MetaSVM -0.89
- CADD 19.00
- PolyPhen-2 0.38
- SIFT 0.18
- Most common in the Latino/Admixed American population (allele frequency 0.00014)
- Structural context available