D42Y (p.Asp42Tyr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
D42Y (p.Asp42Tyr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data, published literature, and structural context.
D42Y (p.Asp42Tyr) variant details
- p.Asp42Tyr
- gnomAD 21-33335571-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.713
- REVEL 0.72
- MetaLR 0.58
- MetaSVM 0.23
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available