D39G (p.Asp39Gly) variant of IFNAR1 (Interferon alpha/beta receptor 1)
D39G (p.Asp39Gly) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
D39G (p.Asp39Gly) variant details
- p.Asp39Gly
- gnomAD 21-33335563-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.21
- MetaLR 0.24
- MetaSVM -0.94
- CADD 3.58
- PolyPhen-2 0.12
- SIFT 0.71
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available