A25T (p.Ala25Thr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
A25T (p.Ala25Thr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
A25T (p.Ala25Thr) variant details
- p.Ala25Thr
- gnomAD 21-33325128-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.31
- MetaLR 0.38
- MetaSVM -0.39
- CADD 23.00
- PolyPhen-2 0.61
- SIFT 0.50
- Population evidence available
- Structural context available
- Literature evidence available