A24D (p.Ala24Asp) variant of IFNAR1 (Interferon alpha/beta receptor 1)
A24D (p.Ala24Asp) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A24D (p.Ala24Asp) variant details
- p.Ala24Asp
- gnomAD 21-33325126-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.47
- MetaLR 0.58
- MetaSVM -0.30
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available