A23T (p.Ala23Thr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
A23T (p.Ala23Thr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A23T (p.Ala23Thr) variant details
- p.Ala23Thr
- TOPMed rs1219830561
- gnomAD rs1219830561
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.29
- MetaLR 0.42
- MetaSVM -0.26
- CADD 22.80
- PolyPhen-2 0.73
- SIFT 0.82
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available