A17S (p.Ala17Ser) variant of IFNAR1 (Interferon alpha/beta receptor 1)
A17S (p.Ala17Ser) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- TOPMed rs2083113169
- gnomAD rs2083113169
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.12
- MetaLR 0.26
- MetaSVM -0.95
- CADD 9.60
- PolyPhen-2 0.08
- SIFT 0.78
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available