A15S (p.Ala15Ser) variant of IFNAR1 (Interferon alpha/beta receptor 1)
A15S (p.Ala15Ser) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
A15S (p.Ala15Ser) variant details
- p.Ala15Ser
- gnomAD 21-33325098-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.375
- REVEL 0.17
- MetaLR 0.36
- MetaSVM -0.72
- CADD 14.60
- PolyPhen-2 0.33
- SIFT 0.78
- Population evidence available
- Structural context available
- Literature evidence available