Y4S (p.Tyr4Ser) variant of IDH2 (P48735)
Y4S (p.Tyr4Ser) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Y4S (p.Tyr4Ser) variant details
- p.Tyr4Ser
- Ensembl rs2151558092
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.38
- CADD 23.80
- PolyPhen-2 0.27
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available