T115S (p.Thr115Ser) variant of IDH2 (P48735)
T115S (p.Thr115Ser) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
T115S (p.Thr115Ser) variant details
- p.Thr115Ser
- Ensembl rs1007176774
- Missense
- Variant Prioritization Score for Impact Estimate 0.75
- REVEL 0.73
- CADD 26.50
- PolyPhen-2 0.72
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available