S31P (p.Ser31Pro) variant of IDH2 (P48735)
S31P (p.Ser31Pro) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S31P (p.Ser31Pro) variant details
- p.Ser31Pro
- Ensembl rs2151558000
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.17
- CADD 18.50
- PolyPhen-2 0.02
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 4e-05)
- Structural context available