S17W (p.Ser17Trp) variant of IDH2 (P48735)
S17W (p.Ser17Trp) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S17W (p.Ser17Trp) variant details
- p.Ser17Trp
- gnomAD rs1396836085
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.33
- CADD 22.10
- PolyPhen-2 0.26
- SIFT 0.01
- Population evidence available
- Structural context available