S15P (p.Ser15Pro) variant of IDH2 (P48735)
S15P (p.Ser15Pro) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S15P (p.Ser15Pro) variant details
- p.Ser15Pro
- Ensembl rs2151558055
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.18
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 4.1e-06)
- Structural context available