S108N (p.Ser108Asn) variant of IDH2 (P48735)
S108N (p.Ser108Asn) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S108N (p.Ser108Asn) variant details
- p.Ser108Asn
- ExAC rs773592372
- gnomAD rs773592372
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.12
- CADD 8.62
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available