P87S (p.Pro87Ser) variant of IDH2 (P48735)
P87S (p.Pro87Ser) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
P87S (p.Pro87Ser) variant details
- p.Pro87Ser
- cosmic curated COSV57482
- Ensembl rs2151551296
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.27
- CADD 24.00
- PolyPhen-2 0.74
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available