P35L (p.Pro35Leu) variant of IDH2 (P48735)
P35L (p.Pro35Leu) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- TOPMed rs886385060
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.10
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 0.38
- Population evidence available
- Structural context available