L86F (p.Leu86Phe) variant of IDH2 (P48735)
L86F (p.Leu86Phe) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L86F (p.Leu86Phe) variant details
- p.Leu86Phe
- Ensembl rs2151551302
- Missense
- Variant Prioritization Score for Impact Estimate 0.682
- REVEL 0.61
- CADD 26.70
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available