L26P (p.Leu26Pro) variant of IDH2 (P48735)
L26P (p.Leu26Pro) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L26P (p.Leu26Pro) variant details
- p.Leu26Pro
- gnomAD rs1212451541
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.13
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.8e-05)
- Structural context available