L11R (p.Leu11Arg) variant of IDH2 (P48735)
L11R (p.Leu11Arg) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
L11R (p.Leu11Arg) variant details
- p.Leu11Arg
- TOPMed rs1258065873
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- REVEL 0.47
- CADD 22.10
- PolyPhen-2 0.05
- SIFT 0.08
- Population evidence available
- Structural context available