K67T (p.Lys67Thr) variant of IDH2 (P48735)
K67T (p.Lys67Thr) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
K67T (p.Lys67Thr) variant details
- p.Lys67Thr
- ExAC rs759030336
- gnomAD rs759030336
- Missense
- Variant Prioritization Score for Impact Estimate 0.764
- REVEL 0.83
- CADD 29.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available