K67R (p.Lys67Arg) variant of IDH2 (P48735)
K67R (p.Lys67Arg) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
K67R (p.Lys67Arg) variant details
- p.Lys67Arg
- ExAC rs759030336
- gnomAD rs759030336
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.44
- CADD 24.30
- PolyPhen-2 0.44
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available