K42R (p.Lys42Arg) variant of IDH2 (P48735)
K42R (p.Lys42Arg) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K42R (p.Lys42Arg) variant details
- p.Lys42Arg
- gnomAD rs1901039396
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.14
- CADD 20.30
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available