K42E (p.Lys42Glu) variant of IDH2 (P48735)
K42E (p.Lys42Glu) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K42E (p.Lys42Glu) variant details
- p.Lys42Glu
- Ensembl rs758194887
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.15
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available