G3R (p.Gly3Arg) variant of IDH2 (P48735)
G3R (p.Gly3Arg) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G3R (p.Gly3Arg) variant details
- p.Gly3Arg
- ExAC rs755082688
- gnomAD rs755082688
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.44
- CADD 23.00
- PolyPhen-2 0.75
- SIFT 0.08
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available