G16S (p.Gly16Ser) variant of IDH2 (P48735)
G16S (p.Gly16Ser) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
G16S (p.Gly16Ser) variant details
- p.Gly16Ser
- ExAC rs762573949
- TOPMed rs762573949
- gnomAD rs762573949
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.16
- CADD 13.90
- PolyPhen-2 0.02
- SIFT 0.80
- Most common in the South Asian population (allele frequency 3.4e-05)
- Structural context available