E68G (p.Glu68Gly) variant of IDH2 (P48735)
E68G (p.Glu68Gly) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
E68G (p.Glu68Gly) variant details
- p.Glu68Gly
- gnomAD rs1901036665
- Missense
- Variant Prioritization Score for Impact Estimate 0.748
- REVEL 0.82
- CADD 29.00
- PolyPhen-2 0.38
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available