E33K (p.Glu33Lys) variant of IDH2 (P48735)
E33K (p.Glu33Lys) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- gnomAD rs1171749840
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.14
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.91
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available