D119V (p.Asp119Val) variant of IDH2 (P48735)
D119V (p.Asp119Val) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
D119V (p.Asp119Val) variant details
- p.Asp119Val
- gnomAD rs1280950562
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- REVEL 0.86
- CADD 32.00
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available