C12Y (p.Cys12Tyr) variant of IDH2 (P48735)
C12Y (p.Cys12Tyr) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
C12Y (p.Cys12Tyr) variant details
- p.Cys12Tyr
- Ensembl rs2151558066
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.19
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available