A2T (p.Ala2Thr) variant of IDH2 (P48735)
A2T (p.Ala2Thr) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- Ensembl rs2151558099
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.40
- CADD 20.80
- PolyPhen-2 0.07
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available