A25G (p.Ala25Gly) variant of IDH2 (P48735)
A25G (p.Ala25Gly) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A25G (p.Ala25Gly) variant details
- p.Ala25Gly
- TOPMed rs1371083762
- gnomAD rs1371083762
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.08
- CADD 19.30
- PolyPhen-2 0.02
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available