A25D (p.Ala25Asp) variant of IDH2 (P48735)
A25D (p.Ala25Asp) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A25D (p.Ala25Asp) variant details
- p.Ala25Asp
- TOPMed rs1371083762
- gnomAD rs1371083762
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.13
- CADD 22.60
- PolyPhen-2 0.02
- SIFT 0.03
- Population evidence available
- Structural context available