A22T (p.Ala22Thr) variant of IDH2 (P48735)
A22T (p.Ala22Thr) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- gnomAD rs1282863956
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.13
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Middle Eastern population (allele frequency 0.00027)
- Structural context available