A22S (p.Ala22Ser) variant of IDH2 (P48735)
A22S (p.Ala22Ser) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A22S (p.Ala22Ser) variant details
- p.Ala22Ser
- gnomAD rs1282863956
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.13
- CADD 14.50
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the Latino/Admixed American population (allele frequency 8.8e-05)
- Structural context available