A110P (p.Ala110Pro) variant of IDH2 (P48735)
A110P (p.Ala110Pro) in IDH2 (P48735) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
A110P (p.Ala110Pro) variant details
- p.Ala110Pro
- ESP rs368655225
- ExAC rs368655225
- TOPMed rs368655225
- gnomAD rs368655225
- Missense
- Variant Prioritization Score for Impact Estimate 0.767
- REVEL 0.76
- CADD 27.70
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available