V35A (p.Val35Ala) variant of IDH1 (O75874)
V35A (p.Val35Ala) in IDH1 (O75874) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
V35A (p.Val35Ala) variant details
- p.Val35Ala
- ExAC rs757444051
- TOPMed rs757444051
- gnomAD rs757444051
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.72
- CADD 26.70
- PolyPhen-2 0.46
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available