T19A (p.Thr19Ala) variant of IDH1 (O75874)
T19A (p.Thr19Ala) in IDH1 (O75874) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
T19A (p.Thr19Ala) variant details
- p.Thr19Ala
- cosmic curated COSV61617
- ExAC rs11554138
- gnomAD rs11554138
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- REVEL 0.79
- CADD 26.90
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available