L25F (p.Leu25Phe) variant of IDH1 (O75874)
L25F (p.Leu25Phe) in IDH1 (O75874) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L25F (p.Leu25Phe) variant details
- p.Leu25Phe
- Ensembl rs2124868138
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.35
- CADD 17.30
- PolyPhen-2 0.60
- SIFT 1.00
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available