F32C (p.Phe32Cys) variant of IDH1 (O75874)
F32C (p.Phe32Cys) in IDH1 (O75874) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
F32C (p.Phe32Cys) variant details
- p.Phe32Cys
- gnomAD rs1688121732
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.41
- CADD 27.20
- PolyPhen-2 0.84
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available