Y28* (p.Tyr28Ter) variant of ICOS (Inducible T-cell costimulator)
Y28* (p.Tyr28Ter) in ICOS (Inducible T-cell costimulator) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
Y28* (p.Tyr28Ter) variant details
- p.Tyr28Ter
- gnomAD 2-203955661-T-G
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.314
- CADD 33.00
- Population evidence available
- Structural context available
- Literature evidence available