V17S (p.Val17Ser) variant of ICOS (Inducible T-cell costimulator)
V17S (p.Val17Ser) in ICOS (Inducible T-cell costimulator) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
V17S (p.Val17Ser) variant details
- p.Val17Ser
- gnomAD 2-203936859-T-TA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.452
- CADD 22.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available