T19K (p.Thr19Lys) variant of ICOS (Inducible T-cell costimulator)
T19K (p.Thr19Lys) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T19K (p.Thr19Lys) variant details
- p.Thr19Lys
- Ensembl rs1689660635
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.05
- MetaLR 0.12
- MetaSVM -1.03
- CADD 5.52
- PolyPhen-2 0.01
- SIFT 0.23
- Population evidence available
- Structural context available