S93T (p.Ser93Thr) variant of ICOS (Inducible T-cell costimulator)
S93T (p.Ser93Thr) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S93T (p.Ser93Thr) variant details
- p.Ser93Thr
- gnomAD rs1209047569
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.09
- MetaLR 0.11
- MetaSVM -1.01
- CADD 22.40
- PolyPhen-2 0.99
- SIFT 0.34
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available