S91R (p.Ser91Arg) variant of ICOS (Inducible T-cell costimulator)
S91R (p.Ser91Arg) in ICOS (Inducible T-cell costimulator) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
S91R (p.Ser91Arg) variant details
- p.Ser91Arg
- rs1559035890
- gnomAD 2-203955848-A-AG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.408
- CADD 25.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available